Additional general adult spasticity dosing information is also applicable to pediatric spasticity patients.
Acetylcholine activates muscles, so blocking it causes muscle relaxation and paralysis. Botox injections place botulinum toxin directly into a specific muscle. There it has a direct effect on acetylcholine in nerve synapses, blocking signals that would normally cause the muscle to contract.
No definitive serious adverse event reports of distant spread of toxin effect associated with BOTOX for blepharospasm at the recommended dose (30 Units and below), severe primary axillary hyperhidrosis at the recommended dose (cem Units), strabismus, or for chronic migraine at the labeled doses have been reported.
Treatment with botulinum toxins may weaken neck muscles that serve as accessory muscles of ventilation. This may result in a critical loss of breathing capacity in patients with respiratory disorders who may have become dependent upon these accessory muscles.
Interactions between RADIESSE® or RADIESSE® (+) and drugs or other substances or implants Use during pregnancy, or in breastfeeding women
At a minimum, consider a diluted instillation of local anesthetic for all age groups. If a local anesthetic instillation is performed, drain and irrigate the bladder with sterile saline before injection.
Note that this list is not all-até mesmo and includes only common medications that may interact with Botox. You should refer to the prescribing information for Botox for a complete list of interactions.
Botox Cosmetic and Botox come as separate products but are both prescription medicines that contain the active ingredient onabotulinumtoxinA. radiesse Continue reading
The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated for spasticity and other conditions, and particularly in those patients who have an underlying condition that would predispose them to these symptoms. In unapproved uses and in approved indications, symptoms consistent with spread of toxin effect have been reported at doses comparable to or lower than doses used to treat cervical dystonia and spasticity. Patients or caregivers should be advised to seek immediate medical care if swallowing, speech or respiratory disorders occur.
Patients with smaller neck muscle mass and patients who require bilateral injections into the sternocleidomastoid muscle for the treatment of cervical dystonia have been reported to be at greater risk for dysphagia.
Heaviness or Drooping: Too much Botox in the forehead can sometimes cause the brows to feel heavy or even lead to brow ptosis (drooping). Similarly, incorrect placement or dosage around the eyes can lead to eyelid ptosis (drooping eyelid)
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The initial dose for a patient without prior use of BOTOX should be at a lower dose, with subsequent dosing adjusted based on individual response. Limiting the Completa dose injected into the sternocleidomastoid muscle to cem Units or less may decrease the occurrence of dysphagia.
Start conservatively if you're new to Botox. It's often easier to add a little more in a follow-up appointment than to correct an overdone result (which requires waiting for the Botox to wear off naturally, usually over 3-4 months).